Peptide Stacks: How to Combine for Maximum Results

In the world of peptide research, individual compounds often steal the spotlight—whether it’s BPC-157 for recovery, Tirzepatide for weight management, or NAD+ for cellular energy. But more and more researchers are exploring what happens when you combine peptides into strategic stacks. The concept is simple: when two or more peptides complement each other’s mechanisms, the result can be greater than the sum of its parts.

Below, we’ll break down some of the most popular research stack categories and the thought process behind them.

🔥 Fat Loss Stacks

Research into peptides that support metabolic function and fat breakdown is rapidly expanding. Two of the most studied approaches involve combining GLP-1 receptor agonists with metabolic boosters.

GLP-1 + Lipo-C

GLP-1 peptides (like Tirzepatide or Retatrutide) are being studied for appetite regulation and insulin sensitivity.

Lipo-C injections, researched for their role in fat mobilization and liver support, may complement this effect.

Together, they represent a multi-angle approach to supporting fat metabolism.

AOD-9604 + CJC/Ipamorelin

AOD-9604 is a fragment of growth hormone studied for its lipolytic (fat-burning) activity without affecting blood sugar.

Pairing it with GHRP/GHRH peptides (like CJC-1295 and Ipamorelin) may provide a synergistic effect in metabolism and recovery.

💪 Recovery & Repair Stacks

Tissue healing, joint support, and overall recovery are some of the most exciting areas of peptide research.

BPC-157 + TB-500

BPC-157 is being studied for gut health, tendon repair, and injury recovery.

TB-500 (Thymosin Beta-4 fragment) is explored for its role in angiogenesis (blood vessel growth) and tissue repair.

When stacked, researchers hypothesize they may accelerate healing processes on multiple levels.

Glutathione + BPC-157

Glutathione is a master antioxidant.

Combined with BPC-157, this stack is explored for supporting both oxidative stress reduction and physical recovery.

⚡ Energy & Longevity Stacks

Cellular energy and anti-aging research is pushing peptides into the longevity spotlight.

NAD+ + MOTS-C + SS-31

NAD+ is central to cellular energy production.

MOTS-C is being studied as a mitochondrial-targeted peptide supporting energy balance.

SS-31 is researched for mitochondrial protection.

Together, this trio forms a powerhouse “mitochondrial stack” for longevity research.

🧠 Brain & Focus Stacks

Mental clarity, focus, and stress resilience are areas of high interest in peptide science.

Semax + Selank

Semax is studied for neuroprotection and cognitive function.

Selank is explored for its anti-anxiety and calming effects.

Researchers often stack these two for balanced support of focus and stress management.

DSIP + Semax/Selank

DSIP (Delta Sleep-Inducing Peptide) is being studied for sleep quality.

When combined with nootropic peptides, it may help balance stimulation during the day with restorative sleep at night.

📌 Final Thoughts

Peptide stacks are at the frontier of research, offering fascinating opportunities for synergy. While each peptide has unique properties, the real magic often happens when they’re combined thoughtfully.

At The Pept Haus, we believe education is key. Whether you’re exploring fat loss research, recovery applications, or cognitive support, understanding how stacks interact gives you a clearer picture of this fast-growing field.

Stay curious, stay informed, and remember: peptide science is just beginning to show its full potential.